Anoctamin 5/TMEM16E facilitates muscle precursor cell fusion
نویسندگان
چکیده
منابع مشابه
Muscle Differentiation: Signalling Cell Fusion
Myoblast fusion is fundamental both to the production of skeletal muscle during development and to its repair later in life. An in-depth knowledge of cell fusion in general, and myoblast fusion in particular, may also become crucial to developing clinical approaches to tissue repair based on stem cells and/or gene therapy [1,2]. But despite its importance, much remains to be learnt about cell f...
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Muscle precursor cells (MPCs) are required for the regrowth, regeneration, and/or hypertrophy of skeletal muscle, which are deficient in sarcopenia. In the present investigation, we have addressed the issue of age-associated changes in MPC differentiation. MPCs, including satellite cells, were isolated from both young and old rat skeletal muscle with a high degree of myogenic purity (>90% MyoD ...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 2018
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.201812097